Into what estate did the fall bring mankind?

The fall brought mankind into an estate of sin and misery.

Romans 5:12 (NASB)
Therefore, just as through one man sin entered into the world, and death through sin, and so death spread to all men, because all sinned—

I have spent the past twenty-four years working at the bedside as a Registered Nurse. I spent the majority of that time in the Cardiovascular Intensive Care Unit. During that time, I have witnessed human death more than a thousand times; in every instance, death is a horrible, horrible thing. Death is not the natural end of life but a curse on human life because of sin.

Death is threefold:
First, spiritual death, separation from God.
Second, physical death, separation from the body.
Third, eternal death, abandonment in hell.

In this life we have many trials and tribulations because of the curse, and our bodies are dying and decaying.